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metronidazole will enhance the amount or outcome of bortezomib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.elvitegravir/cobicistat/emtricitabine/tenofovir DF will increase amounts of bortezomib by influencing hepatic/intestinal enzyme CYP3A4 metabolism.Check Closely (one)mitotane decreases amounts of bortezomib by

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